Drawn from the same murky well of Hollywood ethical ambiguity that gave us 'Thank You for Smoking' and last year's 'Up in the Air,' 'Love & Other Drugs' audaciously defines its slick anti-hero protagonist as beyond reproach. The filmmakers are clearly banking on the allure of nude sex scenes between Jake Gyllenhaal and Anne Hathaway to attract audiences, but the love story (and sex scenes) don't amount to much. Grade: C.
Writer/director Nicole Holofcener drops yet another urbane, talky, existentially searching comedy armed with the kind of character and emotional nuance Woody Allen lost years ago. Catherine Keener and Oliver Platt play a fortysomething married couple with an angsty teenage daughter and a flourishing furniture store in Manhattan who drift apart as their material possessions grow in number and lavishness. Grade: B-plus.