In Don't Cross the Streams, a popular early '80s film about ghosts and people who bust them is receiving a stage musical adaptation by a New Jersey theatre company. When their world is shattered by a "cease and desist" letter from the lawyers of Columbia Pictures, the cast and crew give the show a new title, make delirious changes to an increasingly unrecognizable script and recruit a handsomely clueless soap opera actor to play the role of Peter Venkman. Silly string ion streams are unleashed and a giant Twinkie kicks a man in the groin in a madcap theatrical farce a la "Waiting for Guffman."